Appointment of Chief Executive Officer

This Release Contains Inside Information.

Slough, United Kingdom and Richmond, Virginia – June 29, 2020 – Indivior PLC (LON: INDV)
announces that effective today, the Board of Directors has appointed Mark Crossley as Chief
Executive Officer. Shaun Thaxter, in mutual agreement with the Board, is stepping down as Chief
Executive Officer and Executive Director.

Mr. Crossley has been Chief Financial and Operations Officer (CFOO) and Executive Director of
Indivior since February 2017. He was previously Chief Strategy Officer from 2014-2017 and served as
Finance Director where he led the demerger of Indivior from its former parent. Prior to joining
Indivior in 2012, Mark spent thirteen years at Procter & Gamble in various finance leadership
positions and eight years as an officer in the United States Coast Guard.

Ryan Preblick, currently SVP Global Financial Planning and Analysis Commercial Operations, has been
appointed interim Chief Financial Officer. Indivior will initiate a search for a permanent Chief
Financial Officer and will assess whether to appoint a separate Operations Officer. As an interim
appointee, Mr. Preblick will not be appointed as an Executive Director. Ryan joined Indivior in 2012
as Regional Finance Controller (North America), later becoming VP U.S. Finance, responsible for
Financial Planning & Analysis and Government Pricing. He was promoted to his current role in
January 2020. Previously, he worked for fourteen years in various finance capacities at Altria Group
and Honeywell International.

Comment by Daniel Tassé, Interim Chair of Indivior PLC:
“Indivior’s vision is to ensure patients all around the world have access to evidence-based treatment
for the chronic conditions and co-occurring disorders of addiction. Mark is a proven leader with a
broad strategic and financial skillset and a deep understanding of the Company’s guiding principles.
The Board has full confidence in his ability to drive Indivior forwards and to pursue its vision for the
benefit of all stakeholders. Shaun has played a key role since the formation of Indivior and on behalf
of the Board we thank him for his significant contributions to Indivior and, in particular, his efforts to
advance addiction treatment across our global communities.

“Indivior has a strong culture across all fronts of the business and I and the Board look forward to
supporting Mark, the executive team and all of our colleagues in the months and years ahead.”

Comment by Mark Crossley, CEO of Indivior PLC:
“I am honored to have been appointed as Chief Executive Officer of Indivior as we continue our work
to change patients’ lives by developing medicines to treat addiction and serious mental health
illnesses. In recent years, the Group has made excellent strategic progress on life-transforming
treatments with the launch of SUBLOCADE® and PERSERIS®. There remains a very significant
opportunity for Indivior in the years ahead, and I look forward to working with the Board to deliver
the full potential of our key assets, to resolve outstanding investigations and litigations as
expeditiously as possible, and to ensure that we continue to play a leading role in helping patients,
doctors, and communities fight the human crisis of opioid addiction. Finally, I would like to take a
moment to thank Shaun for his leadership at Indivior and significant contributions within the
addiction treatment community.”

Comment by Shaun Thaxter:
“It has been an honour and a privilege to lead the development of Indivior as it focused on
empowering individuals to overcome their addiction. We have truly been pioneers in developing
new treatments and helping to change patients’ lives. Indivior has a highly talented management
and workforce. I am confident in their ability to deliver against its vision as I prepare for my next
business challenge.”

Remuneration:
Shaun Thaxter will be treated in accordance with Indivior’s approved remuneration policy and the
terms of his service contract. Full details of remuneration payable to Shaun Thaxter will be disclosed
on the Indivior website in compliance with Section 430(2B) of the Companies Act 2006 and will be
disclosed in the Company’s Annual Report and Accounts for the year ending December 31, 2020.

SUBLOCADE® (BUPRENORPHINE EXTENDED-RELEASE) INJECTION FOR SUBCUTANEOUS USE (CIII)
INDICATION AND HIGHLIGHTED SAFETY INFORMATION

INDICATION

SUBLOCADE is indicated for the treatment of moderate to severe opioid use disorder in patients who have initiated treatment with a
transmucosal buprenorphine-containing product, followed by dose adjustment for a minimum of 7 days.

SUBLOCADE should be used as part of a complete treatment plan that includes counselling and psychosocial support.

WARNING: RISK OF SERIOUS HARM OR DEATH WITH INTRAVENOUS ADMINISTRATION; SUBLOCADE RISK EVALUATION AND MITIGATION STRATEGY

• Serious harm or death could result if administered intravenously. SUBLOCADE forms a solid mass upon contact with body fluids and may cause occlusion, local tissue damage, and thrombo-embolic events, including life threatening pulmonary emboli, if administered intravenously.
   
• Because of the risk of serious harm or death that could result from intravenous self-administration, SUBLOCADE is only available through a restricted program called the SUBLOCADE REMS Program. Healthcare settings and pharmacies that order and dispense SUBLOCADE must be certified in this program and comply with the REMS requirements.

HIGHLIGHTED SAFETY INFORMATION
Prescription use of this product is limited under the Drug Addiction Treatment Act.

CONTRAINDICATIONS

SUBLOCADE should not be administered to patients who have been shown to be hypersensitive to buprenorphine or any component of
the ATRIGEL® delivery system.

WARNINGS AND PRECAUTIONS

Addiction, Abuse, and Misuse: SUBLOCADE contains buprenorphine, a Schedule III controlled substance that can be abused in a manner
similar to other opioids. Monitor patients for conditions indicative of diversion or progression of opioid dependence and addictive
behaviours.

Respiratory Depression: Life threatening respiratory depression and death have occurred in association with buprenorphine. Warn
patients of the potential danger of self-administration of benzodiazepines or other CNS depressants while under treatment with
SUBLOCADE.

Neonatal Opioid Withdrawal Syndrome: Neonatal opioid withdrawal syndrome is an expected and treatable outcome of prolonged use of
opioids during pregnancy.

Adrenal Insufficiency: If diagnosed, treat with physiologic replacement of corticosteroids, and wean patient off of the opioid.

Risk of Opioid Withdrawal with Abrupt Discontinuation: If treatment with SUBLOCADE is discontinued, monitor patients for several
months for withdrawal and treat appropriately.

Risk of Hepatitis, Hepatic Events: Monitor liver function tests prior to and during treatment.

Risk of Withdrawal in Patients Dependent on Full Agonist Opioids: Verify that patient is clinically stable on transmucosal buprenorphine
before injecting SUBLOCADE.

Treatment of Emergent Acute Pain: Treat pain with a non-opioid analgesic whenever possible. If opioid therapy is required, monitor
patients closely because higher doses may be required for analgesic effect.

ADVERSE REACTIONS

Adverse reactions commonly associated with SUBLOCADE (in ≥5% of subjects) were constipation, headache, nausea, injection site pruritus,
vomiting, increased hepatic enzymes, fatigue, and injection site pain.

For more information about SUBLOCADE, the full Prescribing Information including BOXED WARNING, and Medication Guide visit
www.sublocade.com.

PERSERIS® (risperidone) for extended-release injectable suspension
INDICATION AND HIGHLIGHTED SAFETY INFORMATION
PERSERIS (risperidone) is indicated for the treatment of schizophrenia in adults.

WARNING: INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED

See full prescribing information for complete boxed warning.

• Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death.
• PERSERIS is not approved for use in patients with dementia-related psychosis

CONTRAINDICATIONS

PERSERIS should not be administered to patients with known hypersensitivity to risperidone, paliperidone, or other components of
PERSERIS.

WARNINGS AND PRECAUTIONS

Cerebrovascular Adverse Reactions, Including Stroke in Elderly Patients with Dementia-Related Psychosis: Increased risk of
cerebrovascular adverse reactions (e.g., stroke, transient ischemic attack), including fatalities. PERSERIS is not approved for use in patients
with dementia-related psychosis.

Neuroleptic Malignant Syndrome (NMS): Manage with immediate discontinuation and close monitoring.

Tardive Dyskinesia: Discontinue treatment if clinically appropriate.

Metabolic Changes: Monitor for hyperglycemia, dyslipidemia and weight gain.

Hyperprolactinemia: Prolactin elevations occur and persist during chronic administration. Long-standing hyperprolactinemia, when
associated with hypogonadism, may lead to decreased bone density in females and males.

Orthostatic Hypotension: Monitor heart rate and blood pressure and warn patients with known cardiovascular disease or cerebrovascular
disease, and risk of dehydration or syncope.

Leukopenia, Neutropenia, and Agranulocytosis: Perform complete blood counts (CBC) in patients with a history of a clinically significant
low white blood cell count (WBC) or history of leukopenia or neutropenia. Consider discontinuing PERSERIS if a clinically significant decline
in WBC occurs in absence of other causative factors.

Potential for Cognitive and Motor Impairment: Use caution when operating machinery.

Seizures: Use caution in patients with a history of seizures or with conditions that lower the seizure threshold.

ADVERSE REACTIONS
The most common adverse reactions in clinical trials (≥ 5% and greater than twice placebo) were increased weight, sedation/somnolence
and musculoskeletal pain. The most common injection site reactions (≥ 5%) were injection site pain and erythema (reddening of the skin).

For more information about PERSERIS, the full Prescribing Information including BOXED WARNING, and Medication Guide visit
www.perseris.com.

Forward-Looking Statements

This announcement contains certain statements that are forward-looking. By their nature, forward-looking statements involve risks and uncertainties as they relate to events or circumstances that may or may not occur in the future. Actual results may differ materially from those expressed or implied in such statements because they relate to future events. Forward-looking statements include, among other things, statements regarding the Indivior Group’s financial guidance for 2020, if any, and its medium- and long-term growth outlook, its operational goals, its product development pipeline and statements regarding ongoing litigation and other statements containing the words "subject to", "believe", "anticipate", "plan", "expect", "intend", "estimate", "project", "may", "will", "should", "would", "could", "can", the negatives thereof, variations thereon and similar expressions.

Various factors may cause differences between Indivior's expectations and actual results, including, among others
(including those described in the risk factors described in the most recent Indivior PLC Annual Report and in subsequent releases): factors affecting sales of Indivior Group’s products and financial position; the outcome of research and 
development activities; decisions by regulatory authorities regarding the Indivior Group’s drug applications or
authorizations; the speed with which regulatory authorizations, pricing approvals and product launches may be achieved, if at all; the outcome of post-approval clinical trials; competitive developments; difficulties or delays in manufacturing and in the supply chain; disruptions in or failure of information technology systems; the impact of existing and future legislation and regulatory provisions on product exclusivity; trends toward managed care and healthcare cost containment; legislation or regulatory action affecting pharmaceutical product pricing, reimbursement or access; challenges in the commercial execution; claims and concerns that may arise regarding the safety or efficacy of the Indivior Group’s products and product candidates; risks related to legal proceedings, including the indictment by the U.S. Department of Justice, potential exclusion from participating in U.S. Federal Health Care Programs; the ongoing investigative and antitrust litigation matters; the opioid national multi-district litigation and securities class action litigation; the Indivior Group’s ability to protect its patents and other intellectual property; the outcome of patent infringement litigation relating to Indivior Group’s products, including the ongoing ANDA lawsuits; changes in governmental laws and regulations; issues related to the outsourcing of certain operational and staff functions to third parties; risks related to the evolving COVID-19 pandemic and the potential impact of COVID-19 on the Indivior Group’s operations and financial condition, which cannot be predicted with confidence; uncertainties related to general economic, political, business, industry, regulatory and market conditions; and the impact of acquisitions, divestitures, restructurings, internal reorganizations, product recalls and withdrawals and other unusual items.

Consequently, forward-looking statements speak only as of the date that they are made and should be regarded solely as our current plans, estimates and beliefs. You should not place undue reliance on forward-looking statements. We cannot guarantee future results, events, levels of activity, performance or achievements. Except as required by law, we do not undertake and specifically decline any obligation to update, republish or revise forward-looking statements to reflect future events or circumstances or to reflect the occurrences of unanticipated events.
 

About Indivior
Indivior is a global pharmaceutical company working to help change patients’ lives by developing
medicines to treat addiction and serious mental illnesses. Our vision is that all patients around the world
will have access to evidence-based treatment for the chronic conditions and cooccurring disorders of
addiction. Indivior is dedicated to transforming addiction from a global human crisis to a recognized and
treated chronic disease. Building on its global portfolio of opioid dependence treatments, Indivior has a
pipeline of product candidates designed to both expand on its heritage in this category and potentially
address other chronic conditions and co-occurring disorders of addiction, including alcohol use disorder.
Headquartered in the United States in Richmond, VA, Indivior employs more than 800 individuals
globally and its portfolio of products is available in over 40 countries worldwide. Visit www.indivior.com
to learn more. Connect with Indivior on LinkedIn by visiting www.linkedin.com/company/indivior.

Media Contacts
US
IndiviorMediaContacts@indivior.com
+1 804-594-0836

UK
Tulchan Communications
+44 207-353-4200

Investor Contact
Jason Thompson
Indivior Vice President, Investor Relations
+1 804-402-7123
Jason.Thompson@indivior.com